What is the application of polyhexamethylene biguanidine hydrochloride (PHMB)?

Introduction of Polyhexamethylene biguanide hydrochloride (PHMB)

Polyhexamethylene biguanide hydrochloride (PHMB) solution system is a chemical disinfectant newly developed and researched in recent years. Scientific research has shown that it has excellent bactericidal properties, low irritation, low toxicity, low concentration, and fast sterilization, etc.

Applications of Polyhexamethylene biguanide hydrochloride (PHMB)

•  For aquaculture

Polyhexamethylene biguanide hydrochloride (PHMB) is a high molecular polymer that can quickly kill harmful bacteria such as Gram-negative bacteria, Floating Vibrio, Vibrio parahaemolyticus and Vibrio alginolyticus in seawater. It has good preventive and therapeutic effects on various diseases caused by bacteria in sea cucumbers and other aquatic products.

• As an antibacterial finishing agent for fabrics

ICI Company has developed a Reptex20 product with 20% polyhexamethylene biguanide hydrochloride (PHMB) as the active substance, which is applied to the antibacterial and deodorant finishing of textiles. Cotton and its blended fabrics treated with Reptex20 antibacterial agent can effectively inhibit the growth of bacteria, and its antibacterial properties are still effective after multiple washings. Because Reputex20 antibacterial agent is relatively mild and will not cause damage to textiles, it is suitable for most cotton fiber products. The wool fabrics treated with polyhexamethylene biguanide hydrochloride (PHMB) have good bacteriostatic and washing resistance against Staphylococcus aureus.

• Contact lens care solution

At present, most of the contact lens care solutions on the market use polyhexamethylene biguanide hydrochloride (PHMB) and polyaminopropyl biguanide salt (PAPB) as the main active ingredients. The contact lens care solution with polyhexamethylene biguanide hydrochloride (PHMB) as the main component acts on Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa for 2 hours, and the log kill value is all greater than 3.00; Fusarium and Candida albicans were treated for 2 h, and the logarithmic killing values were all greater than 1.00. According to GB19192-2003 Sanitary Requirements for Contact Lens Care Solutions, polyhexamethylene biguanide hydrochloride (PHMB) can be used in cleaning, disinfection, preservation and lubrication products for contact lenses.

• For disinfection wipes

Polyhexamethylene biguanide hydrochloride (PHMB) can not only be used to prepare disinfectant wipes, but also an ideal raw material for antibacterial wipes, antibacterial wipes and personal care wipes. Excellent substitute for similar products. It is a cationic polymer, and its antibacterial effect is mainly by dissolving lipids, changing the permeability of bacterial cell membranes, and causing obstacles to metabolism in bacteria and antibacterial. It has a wide antibacterial spectrum and is effective against Gram-positive and negative bacteria and molds. It is colorless, odorless, non-irritating to the skin, non-toxic and non-corrosive. Therefore, the wet wipes treated with it can achieve a rapid disinfection effect without mildew, and the shelf life can be up to two years.