CAS:5909-24-0 | Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate
Molecular Formula:C8H9ClN2O2S
Molecular Weight:232.69g/mol
EINECS:227-619-0
Purity:98%
Package:5g/10g/25g/50g/bulk package
Transportation:FeDex/DHL/Ocean shipping/Clients requirement
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Product Introduction
Products Description
Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate(CAS:5909-24-0) is a potent inhibitor of tyrosine kinases. It has been shown to inhibit the growth of cancer cells in vitro and in vivo. This drug has also been shown to be effective against various types of human cancer cell lines, such as human leukemia cells and myeloma cells. Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate inhibits the production of proteins vital for cell division by binding to tyrosine kinase. This binding prevents the formation of an enzyme complex with other enzymes that are required for protein synthesis, thereby inhibiting protein synthesis and cell division. The compound has also been shown to be a highly selective inhibitor of amines, which may contribute to its pharmacological effects.
Specification
|
ITEMS |
SPECIFICATION |
|
IUPAC Name |
ethyl 4-chloro-2-methylsulfanylpyrimidine-5-carboxylate |
|
MDL No |
MFCD00006085 |
|
Boiling Point |
335.7±22.0 °C at 760 mmHg |
|
Melting Point |
60-63 °C(lit.) |
|
Flash Point |
156.8±22.3 °C |
|
Density |
1.4±0.1 g/cm3 |
|
PSA |
77.38 |
|
LogP |
2.55 |
|
Appearance |
White to yellow or brown powder |
|
Vapour Pressure |
0.0±0.7 mmHg at 25°C |
|
Refractive index: |
1.568 |
|
Storage condition |
Keep in dark place,Sealed in dry,Room Temperature |
|
InChI |
InChI=1S/C8H9ClN2O2S/c1-3-13-7(12)5-4-10-8(14-2)11-6(5)9/h4H,3H2,1-2H3 |
|
InChIKey |
SNNHLSHDDGJVDM-UHFFFAOYSA-N |
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