CAS:69-72-7 | Salicylic Acid

Name:Salicylic acid

Synonyms:2-hydroxybenzoic acid

CAS:69-72-7

Purity:99%

Molecular Formula:C₇H₆O₃

Molecular Weight:138.12

Melting Point:158-161° C (lit.)

Boiling Point:211° C (lit.)

Flash Point:157°C (315°F)

Density:1.44 g/cm³

Appearance:White powder or crystals

Sensitivity:Light Sensitive

Stability:Stable. Substances to be avoided include oxidizing agents, strong bases, iodine, fluorine. Combustible. Sensitive to light.

Solubility:Soluble in carbon terachloride, benzene, propanol, absolute ethanol, acetone, toluene and ether.

Water solubility:1.8 g/L

pKa:2.98(at 25℃)

refractive index:1,565

Storage condition:Store at room temperature

Application:Salicylic acid(CAS:69-72-7) is a natural product extract from Willow bark, well known as an antiinflammatory and antinociceptive agent and a close structural relative to acetylsalicylic acid (aspirin). Salicylic acid is a ubiquitous plant hormone with many regulatory functions involved in local disease resistance mechanisms and systemic acquired resistance. The antiinflammatory and antinociceptive effects produced by Salicylic acid and its derivatives in animals are due to inhibition of COX-1 and COX-2 (cyclooxygenase) enzyme activity and suppression of prostaglandin biosynthesis. Salicylic acid is also of interest as a starting material for the organic synthesis of more elaborate COX suppressors and other chemical structures.

Reference: 

1. Delaney, T.P., et al. 1994. Science. 266: 1247-1250. PMID: 17810266

2. Steen, K.H., et al. 1996. Pain. 64: 71-82. PMID: 8867248

3. Mitchell, J.A., et al. 1997. Mol. Pharmacol. 51: 907-912. PMID: 9187256

4. Vane, J.R. and Botting, R.M. 1998. Am. J. Med. 104: 2S-21S. PMID: 9572314

5. Vlot, A.C., et al. 2009. Annu Rev Phytopathol. 47: 177-206. PMID: 19400653

Packaging & Delivery

Package:100g/500g/1kg/bulk package

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