CAS:58186-27-9 | Idebenone

Name:Idebenone

Synonyms:2-(10-Hydroxydecyl)-5,6-dimethoxy-3-methyl-2,5-cyclohexadiene-1,4-dione

CAS:58186-27-9

Purity:98%

Molecular Formula:C₁₉H₃₀O₅

Molecular Weight:338.44

Melting Point:192.68° C (Predicted)

Boiling Point:497.3° C at 760 mmHg (Predicted)

Flash Point:170.1°C

Density:1.08 g/cm³ (Predicted)

Appearance:Yellow to orange solid,powder or crystals

Solubility:Soluble in DMSO (>25 mg/ml), ethanol (>25 mg/ml), methanol, and chloroform

Water solubility:Insoluble

pKa:15.19

refractive index:1.50

Vapor Presure:5.67E-12mmHg at 25°C

Storage condition:Store at room temperature

InChi:InChI=1S/C19H30O5/c1-14-15(12-10-8-6-4-5-7-9-11-13-20)17(22)19(24-3)18(23-2)16(14)21/h20H,4-13H2,1-3H3

InChi Key:JGPMMRGNQUBGND-UHFFFAOYSA-N

Application:Idebenone(CAS:58186-27-9), a neuroprotective agent, has been shown to act as a free radical scavenger and protect mitochondrial membranes against lipid peroxidation. This compound has also been found to prevent platelet aggregation and recover cholinergic and monoaminergic changes in murine models. Other studies show that Idebenone displays a capacity to increase nerve growth factor production in cultured rat astrocytes. Additionally, this agent has been reported to dose-dependently inhibit enzymatic metabolism of Arachidonic Acid (sc-200770) in astroglial homogenates.

Reference: 

1. Zs -Nagy, I. 1990. Arch Gerontol Geriatr. 11: 177-186. PMID: 15374467

2. Civenni, G., et al. 1999. Eur. J. Pharmacol. 370: 161-167. PMID: 10323265

3. Takuma, K., et al. 2000. Eur. J. Pharmacol. 406: 333-339. PMID: 11040339

Packaging & Delivery

Package:10mg/25mg/50mg/bulk package

Transportation: by FeDex or by ocean shipping or clients requirement

Delivery Detail: Within 3-5 days after full payment

Flexible payment terms: support T/T, Paypal , Credit Card

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