CAS:298-93-1 | Thiazolyl Blue

Name:Thiazolyl Blue

Synonyms:MTT, MMT Tetrazolium, Thiazolyl Blue Tetrazolium Bromide

CAS:298-93-1

Purity:98%

Molecular Formula:C₁₈H₁₆BrN₅S

Molecular Weight:414.33

Melting Point:195° C (dec.)

Boiling Point:N/A

Density:1.4886g/cm³ (estimate)

Appearance:Yellow to orange powder

Stability:Light, air and moisture sensitive

Solubility:Soluble in water (20 mg/ml), ethanol (20 mg/ml), 2-methoxyethanol (20 mg/ml), buffered salt solutions (5 mg/ml), culture media (5 mg/ml), and PBS (5 mg/ml)

Water solubility:Slightly soluble

Storage condition:Store under Nitrogen. Ambient temperatures.

Application:Thiazolyl Blue(CAS:298-93-1) is used in measurement of cell proliferation. Produces a yellowish solution that is converted to dark blue, water-insoluble MTT formazan by mitochondrial dehydrogenases of living cells.Thiazolyl Blue tetrazolium bromide is a dye used in measurement of cell proliferation. It is used as a direct indicator of cytotoxicity (such as for screening cancer drugs) and apoptosis. As an electron acceptor, it is utilized for studying nicotinamide adenine dinucleotide phosphate (NADP)-dependent dehydrogenases.

Reference: 

Ma, W.; Xu, A.; Ying, J.; Li, B.; Jin, Y. Biodegradable Core-Shell Copolymer-Phospholipid Nanoparticles for Combination Chemotherapy: An In Vitro Study. J. Biomed. Nanotechnol. 2015, 11 (7), 1193-1200.

Wei, D.; Chen, T.; Yan, M.; Zhao, W.; Li, F.; Cheng, W.; Yuan, L. Synthesis, characterization, antioxidant activity and neuroprotective effects of selenium polysaccharide from Radix hedysari. Carbohydr. Polym. 2015, 125, 161-168.

Packaging & Delivery

Package:5g/10g/25g/50g/bulk package

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