CAS:11011-38-4丨Ascomycin

Ascomycin, whose medicinal mechanism is similar to tacrolimus, can be used in the treatment of autoimmune diseases such as atopic dermatitis, allergic contact dermatitis, psoriasis, lupus erythematosus, lichenus planus, vitiligo, Netherton syndrome and host suppression disease. Ascomycin can bind to immunoaffinity protein Chemicalbook to form a group of FK-loving immunoproteins, which mainly include FKBP-12, FKBP-13 and FKBP-70, among which FKBP-12 (FK-binding protein 12, Immunoaffinity protein 12 is one of the most important proteins to which ascomycin binds.

ASCOMYCIN,STREPTOMYCESHYGROSCOPICUS;ASCOMYCIN,STREPTOMYCESHYGROSCOPICUSVARASCOMYCETICUS;FR-900520;FK-520;IMMUNOMYCIN;AAG;ASCOMYCIN(IMMUNOMYCIN,FR-900520)\INHIBITSCALCINEURIN(PP2B);(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-8-Ethyl-5,6,8,11,12,13Chemicalbook,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone

CAS:11011-38-4

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