CAS:477600-74-1 | N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Name:N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Synonyms:(3R,4R)-Methyl{(4-methylpiperidin-3-yl)(7H-pyrrolo[2,3-d]pyrimidin-4-yl)}amine; N-Methyl-N-[(3R,4R)-4-methyl-3-piperidinyl]-1H-Pyrrolo[2,3-d]pyrimidin-4-amine

CAS:477600-74-1

Purity:95%

Molecular Formula:C₁₃H₁₉N₅

Molecular Weight:245.32

Melting Point:157 - 162°C

Boiling Point:N/A

Appearance:White to Off-White Solid

Solubility:Aqueous Acid (Slightly), Methanol (Slightly), Water (Slightly, Heated)

pKa:13.36±0.50(Predicted)

Storage condition:Keep in dark place, Sealed in dry, 2-8°C

Application:N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a substance used in the identification of related substances in the degradation products of tofacitinib citrate using LC-MS technique for process monitoring and quality assurance. A reagent for the synthesis of Tofacitinib (CP-690,550), a Janus tyrosine kinase (JAK3) specific inhibitor.

Reference: 

Wu, X., et al.: J. Pharm. Biomed. Anal., 143, 17 (2017); Marican, A., et al.: Tetrahedron Lett., 54, 5096 (2013)

Packaging & Delivery

Package:5mg/10mg/25mg/50mg/bulk package

Transportation: by FeDex or by ocean shipping or clients requirement

Delivery Detail: Within 3-5 days after full payment

Flexible payment terms: support T/T, Paypal , Credit Card

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