CAS 753498-25-8 | Indacaterol Maleate
Molecular Formula: C28H32N2O7
Molecular Weight: 508.57
EINECS: 691-329-4
Purity: 97% Min.
Package: 1 g / 5 g / 25 g / 100 g / 1 kg / 25 kg
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Product Introduction
Introduction
Indacaterol (QAB149) is an ultralong-acting β-adrenoceptor agonist with pKi of 7.36 for β1-adrenoceptor and 5.48 for β2-adrenoceptor.
Synthesis of CAS 753498-25-8 | Indacaterol Maleate
Conditions
Stage #1: 8-(phenylmethoxy)-5-[(R)-2-(5,6-diethyl-indan-2-ylamino)-1-hydroxy-ethyl]-(1H)-quinolin-2-one tartrate With 5%-palladium/activated carbon; hydrogen In methanol under 225.023 Torr; Inert atmosphere;
Stage #2: maleic acid In isopropyl alcohol at 70 - 80℃; for 0.5h;
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