CAS 376608-71-8 | (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (2R)-Hydroxy(phenyl)ethanoate
Molecular Formula: C17H17F2NO3
Molecular Weight: 321.32
EINECS: 1308068-626-2
Purity: 97% Min.
Package: 1 g / 5 g / 25 g / 100 g / 1 kg / 25 kg
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Product Introduction
Specification of CAS 376608-71-8 | (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (2R)-Hydroxy(phenyl)ethanoate
ITEMS | SPECIFICATION |
Storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
Synthesis of CAS 376608-71-8 | (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (2R)-Hydroxy(phenyl)ethanoate

Conditions
Stage #1: trans-(1R,2R)-2-(3,4-difluorophenyl)cyclopropanecarboxylic acid With pyridine; thionyl chloride In toluene at 70℃; for 4h;
Stage #2: With sodium azide; tetrabutylammomium bromide; sodium carbonate In water; toluene at 0℃; for 2h;
Stage #3: (R)-Mandelic Acid In ethyl acetate at 17 - 25℃; for 3h;
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