CAS 877397-65-4 | (S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol
Molecular Formula: C8H7Cl2FO
Molecular Weight: 209.04
EINECS: 700-699-9
Purity: 97% Min.
Package: 1 g / 5 g / 25 g / 100 g / 1 kg / 25 kg
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Product Introduction
Introduction
(S)-1-(2,6-dichloro-3-fluorophenyl)ethanol is an intermediate for organic synthesis and chemical and pharmaceutical research and development, mainly used as an intermediate for antitumor drugs, and an intermediate for crizotinib.
Specification of CAS 877397-65-4 | (S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol
ITEMS | SPECIFICATION |
Storage temp. | Sealed in dry,2-8°C |
Color | White |
Form | Solid |
Density | 1.406 g/cm3 |
Boiling point | 261.3 °C |
pka | 13.30 |
CAS DataBase Reference | 877397-65-4 |
Synthesis of CAS 877397-65-4 | (S)-1-(2,6-Dichloro-3-fluorophenyl)ethanol
Conditions
Stage #1: (1S)-1-(2,6-dichloro-3-fluorophenyl)ethyl acetate With sodium methylate In methanol at 0 - 20℃; for 4h;
Stage #2: With sodium acetate; acetic acid In water pH=7;
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