CAS 1051375-16-6 | Dolutegravir (GSK1349572)
Molecular Formula: C20H19F2N3O5
Molecular Weight: 419.38
EINECS:
Purity: 97% Min.
Package: 500 mg / 1 g / 5 g / 25 g / 100 g / 1 kg
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Product Introduction
Introduction
Dolutegravir is a human immunodeficiency virus-like type 1 (HIV-1) integrase strand transfer inhibitor (INSTI), suitable for use in combination with other antiretroviral drugs in adults and over 12 years of age and with a body weight of at least HIV-1 infection in a 40kg child.
Specification of CAS 1051375-16-6 | Dolutegravir (GSK1349572)
ITEMS | SPECIFICATION |
Boiling point | 669.0 °C |
pka | 4.50 |
density | 1.53 |
Synthesis of CAS 1051375-16-6 | Dolutegravir (GSK1349572)
Conditions
With lithium bromide In tetrahydrofuran; methanol; isopropyl alcohol at 60℃; for 6h; Solvent; Large scale;
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