CAS:1195768-06-9 | Dabrafenib Mesylate

Name:dabrafenib mesylate

Synonyms:N-[3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide,methanesulfonic acid;UNII-B6DC89I63E;

CAS:1195768-06-9

Purity:≥98%

Molecular Formula:C₂₄H₂₄F₃N₅O₅S₃

Molecular Weight:615.67

Melting Point:>234ºC (dec.)

Boiling Point:N/A

PSA:210.96

LogP:7.03

Appearance:White to Off-White Solid

Stability:Hygroscopic

Solubility:Soluble to 50 mM in DMSO

Storage condition:Hygroscopic, -20°C Freezer, Under inert atmosphere

Application:Dabrafenib is an inhibitor of mutated BRAF kinase and has clinical activity with a manageable safety profile in clinical trials of phase 1 and 2 in patients with BRAF(V600)-mutated metastatic melanoma.

Reference:

Hauschild, A., et al.: Lancet, 380, 358 (2012); Falchook, G.S., et al.: Lancet, 379, 1893 (2012); Ascierto, P.A., et al.: J. Clin. Oncol., 31, 3205 (2013)

Packaging & Delivery

Package:5g/10g/25g/50g/bulk package

Transportation: by FeDex or by ocean shipping or clients requirement

Delivery Detail: Within 3-5 days after full payment.

Flexible payment terms: support T/T, Paypal , Credit Card.

Zhengzhou Alfa Chemical Co., Ltd. is a large group corporation which engaged in the manufacture of chemicals.Our team has rich experience in organic synthesis, medicinal chemistry, process chemistry, biology and business management .

Hot Tags: cas:1195768-06-9 | dabrafenib mesylate, price, quotation, discount, in stock, for sale, Pharmaceutical Intermediates, Biochemicals