CAS:106627-54-7 | N-Hydroxysulfosuccinimide Sodium Salt

Name:N-Hydroxysulfosuccinimide sodium salt 

Synonyms:Sulfo-NHS; Hydroxy-2,3-dixopyrrolidine-3-sulfonic acid sodium salt; SNHS

CAS:106627-54-7

Purity:≥98%

Molecular Formula:C₄H₄NO₆S•Na

Molecular Weight:217.13

Melting Point:250° C

Boiling Point:N/A

Appearance:Off-white to white powder

Solubility:Soluble in Methanol and Water

Storage condition:Store at 0 - 8 °C

Application:N-Hydroxysulfosuccinimide Sodium Salt(CAS:106627-54-7) is a variant of N-Hydroxysuccinimide (NHS, sc-219162), derivatized with a sulfate group to confer hydrophilicity. N-Hydroxysulfosuccinimide Sodium Salt can be utilized similarly to NHS to activate carboxylic acids of interest to the more reactive succinimidyl esters for coupling, biotinylation, and conjugation with fluorophores. Also used for crosslinking agents.

Reference: 

1. Anjaneyulu, P.S. and Staros, J.V. 1987. Int. J. Pept. Protein Res. 30: 117-124. PMID: 3667072

2. Bhakdi, S., et al. 1989. J. Immunol. Methods. 121: 61-66. PMID: 2754261

3. Slinkin, M.A., et al. 1990. Bioconjug. Chem. 1: 291-295. PMID: 2096922

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