CAS 57103-68-1 | Maytansinol
Molecular Formula: C28H37ClN2O8
Molecular Weight: 565.05
Purity: 97% Min.
Package: 1 g / 5 g / 25 g / 100 g / 1 kg / 25 kg
Worldwide Delivery
- Worldwide Delivery
- Quality Assurance
- 24/7 Customer Service
Product Introduction
Introduction
Maytansinol is the common parent of Maytansinoids, which are esters of the former, and generally show anticancer effects. Maytansinol has been obtained in large quantities by Japanese scholars through fermentation and converted into maytansinoids. Maytan Chemicalbook drugs and their derivatives are very strong inhibitors of microtubule assembly. They can exhibit anti-mitotic effects at the sub-nanomolar level, and their ED50 (effective dose) is 10-5 ~ 10-4μg/mL. is an ideal anticancer drug.
Specification of CAS 57103-68-1 | Maytansinol
ITEMS | SPECIFICATION |
pka | 9.89 |
Melting point | 205-207℃ |
Density | 1.34 g/cm3 |
Storage temp. | Sealed in dry,2-8°C |
Boiling point | 835.8 °C |
Synthesis of CAS 57103-68-1 | Maytansinol
Conditions
With lithium (hydro)trimethoxyaluminate In tetrahydrofuran at -40℃;
Reference
Porter, John; Ding, Yao; Hale, Sarah J.M.; Perrins, Richard D.; Robinson, Angela; Mazanetz, Michael P.; Wu, Yubo; Ma, Yinping; Conlon, Kelly; Coulter, Tom
[Bioorganic and Medicinal Chemistry Letters, 2020, vol. 30, # 24, art. no. 127634]
Hot Tags: cas 57103-68-1 | maytansinol, price, quotation, discount, in stock, for sale
