CAS 4385-76-6 | 4-Pyrid-4-ylbenzoic Acid
Molecular Formula: C12H9NO2
Molecular Weight: 199.21
EINECS:
Purity: 97% Min.
Package: 1 g / 5 g / 25 g / 100 g / 1 kg
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Product Introduction
Introduction
Thioisonicotinamide is an Impurity of Ethionamide with tuberculostatic activity. It can be used as an intermediate in pharmaceutical synthesis, such as the preparation of 2‑ethyl thioisonicotinamide.
Specification of CAS 4385-76-6 | 4-Pyrid-4-ylbenzoic acid
ITEMS | SPECIFICATION |
Melting point | >300°C |
Storage temp. | Inert atmosphere,Room Temperature |
Water Solubility | Slightly soluble in water. |
Density | 1.241 g/cm3 |
Boiling point | 384.3 °C |
CAS DataBase Reference | 4385-76-6(CAS DataBase Reference) |
Synthesis of CAS 4385-76-6 | 4-Pyrid-4-ylbenzoic acid
Conditions
With sodium carbonate In ethanol; water at 90℃; Suzuki coupling; Inert atmosphere;
Reference
Holzer, Marcel; Ziegler, Sigrid; Neugebauer, Alexander; Kronenberger, Bernd; Klein, Christian D.; Hartmann, Rolf W.
[Archiv der Pharmazie, 2008, vol. 341, # 8, p. 478 - 484]
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