CAS 2274-42-2 | Methylsulfonylacetonitrile
Molecular Formula: C3H5NO2S
Molecular Weight: 119.14
EINECS: 218-888-5
Purity: 97% Min.
Package: 1 g / 5 g / 25 g / 100 g / 1 kg
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Product Introduction
Introduction
Methylsulfonylacetonitrile is used in preparation of substituted pyrimidinylamino isoquinoline and naphthyridine compounds as inhibitors of mutant forms of EGFR.
Specification of CAS 2274-42-2 | METHYLSULFONYLACETONITRILE
ITEMS | SPECIFICATION |
Melting point | 81-84 °C(lit.) |
Storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
Color | White to off-white |
Form | Powder or Crystalline Powder |
Density | 1.288 g/cm3 |
Boiling point | 360.6 °C |
Water Solubility | Slightly soluble in water. |
BRN | 969929 |
Synthesis of CAS 2274-42-2 | METHYLSULFONYLACETONITRILE
Conditions
With sodium tungstate (VI) dihydrate; dihydrogen peroxide In methanol; water at 40℃;
Reference
Yang, Chuanbo; Jin, Qingping; Zhang, Hua; Liao, Jian; Zhu, Jin; Yu, Bin; Deng, Jingen
[Green Chemistry, 2009, vol. 11, # 9, p. 1401 - 1405]
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