CAS:62669-70-9 | Rhodamine 123

Name:Rhodamine 123

Synonyms:Rhodamin 123 Chloride; 2-(6-Amino-3-imino-3H-xanthen-9-yl)benzoic acid methyl ester

CAS:62669-70-9

Purity:98%

Molecular Formula:C₂₁H₁₇N₂O₃•Cl

Molecular Weight:380.82

Melting Point:235° C

Boiling Point:N/A

Appearance:Red-brown to brown or dark green powder

Solubility:Soluble in ethanol (20 mg/ml), DMSO, methanol, and water (partly miscible)

Water solubility:Partially soluble

refractive index:1.65(estimate)

Fluorescent:λex 507 nm, λem 529 nm in methanol

Storage condition:Store at -20° C

Application:Rhodamine 123(CAS:62669-70-9) is a cationic dye that emits a green fluorescence. Research observations indicate that Rhodamine 123 can be used to probe the electrochemical gradient in mitochondria, in flow cytometry to detect the activity of P-glycoprotein efflux, and as a compound for P-GP mediating transport. Studies report that Rhodamine 123 can decrease the clonal growth of carcinoma cells in vitro, and that it can associate with placental P-gp. Rhodamine 123 is a substrate of Mdr (P-glycoprotein). Rhodamine 123 is a substrate of MRP1.

Reference: 

1. Bernal, S.D., et al. 1982. Science. 218: 1117-1119. PMID: 7146897

2. Ferlini, C., et al. 2007. Nat Protoc. 2: 3111-3114. PMID: 18079710

3. Kahlert, S., et al. 2008. J. Neurosci. Methods. 171: 87-92. PMID: 18400303

4. Cygalova, L.H., et al. 2009. J. Pharmacol. Exp. Ther. 331: 1118-1125. PMID: 19779128

5. Munić, V., et al. 2010. Eur J Pharm Sci. 41: 86-95. PMID: 20621639

Packaging & Delivery

Package:5g/10g/25g/50g/bulk package

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