CAS: 31364-42-8 KRYPTOFIX(R) 221
CAS No.: 31364-42-8
Formula: C16H32N2O5
Molecular Weight: 332.43600
EINECS: 250-592-1
Purity: 97% Min.
Package: 5 g / 25 g / 100 g
Lead time: In stock
Delivery: DHL/FEDEX/UPS or By sea
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Product Introduction
Introduction
4,7,13,16,21,24-Hexaoxa-1,10-diazabicyclo[8.8.8]hexacosane (Kryptofix 2.2.2) is used in the routine preparation of [18F]-labeled tracers employed in positron emission tomography (PET) imaging. Confirming the absence of Kryptofix in radiopharmaceuticals is a quality control criterion required before they can be released for human use. Analysis of Kryptofix levels using the iodoplatinate spot-test can be complicated by false-positive results due to nitrogen containing tracers and/or false-negative results caused by added stabilizers. To overcome this issue, we have developed a universal TLC method for the rapid and reliable determination of Kryptofix levels in the wide range of fluorine-18 radiopharmaceuticals we prepare, including complex multi-component formulations.
Specification of CAS: 31364-42-8 KRYPTOFIX(R) 221
ITEMS | SPECIFICATION |
color | Pale yellow |
storage temp. | Store at +2°C to +8°C. |
Fp | >230 °F |
refractive index | n20/D 1.5018(lit.) |
form | Liquid |
Water Solubility | Miscible with water. |
density | 1.111 g/mL at 20 °C(lit.) |
Boiling point | 465.4 °C |
pka | 7.23 |
Sensitive | Light Sensitive |
BRN | 616444 |
Related articles of CAS: 31364-42-8 KRYPTOFIX(R) 221
Conductometric studies of calcium ions with kryptofix 221 in mixed MeOH-DMF solvents at different temperatures
Molecular complexes of crown ethers, part 6: Complexes of Cryptand (2, 2, 2) and Kryptofix 5 with some acceptors
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