CAS: 31364-42-8 KRYPTOFIX(R) 221
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CAS: 31364-42-8 KRYPTOFIX(R) 221

CAS: 31364-42-8 KRYPTOFIX(R) 221

CAS No.: 31364-42-8
Formula: C16H32N2O5
Molecular Weight: 332.43600
EINECS: 250-592-1
Purity: 97% Min.
Package: 5 g / 25 g / 100 g
Lead time: In stock
Delivery: DHL/FEDEX/UPS or By sea
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Product Introduction

Introduction
4,7,13,16,21,24-Hexaoxa-1,10-diazabicyclo[8.8.8]hexacosane (Kryptofix 2.2.2) is used in the routine preparation of [18F]-labeled tracers employed in positron emission tomography (PET) imaging. Confirming the absence of Kryptofix in radiopharmaceuticals is a quality control criterion required before they can be released for human use. Analysis of Kryptofix levels using the iodoplatinate spot-test can be complicated by false-positive results due to nitrogen containing tracers and/or false-negative results caused by added stabilizers. To overcome this issue, we have developed a universal TLC method for the rapid and reliable determination of Kryptofix levels in the wide range of fluorine-18 radiopharmaceuticals we prepare, including complex multi-component formulations.

Specification of CAS: 31364-42-8 KRYPTOFIX(R) 221

ITEMS

SPECIFICATION

color

Pale yellow

storage temp.

Store at +2°C to +8°C.

Fp

>230 °F

refractive index

n20/D 1.5018(lit.)

form

Liquid

Water Solubility

Miscible with water.

density

1.111 g/mL at 20 °C(lit.)

Boiling point

465.4 °C

pka

7.23

Sensitive

Light Sensitive

BRN

616444

Related articles of CAS: 31364-42-8 KRYPTOFIX(R) 221

Conductometric studies of calcium ions with kryptofix 221 in mixed MeOH-DMF solvents at different temperatures

Molecular complexes of crown ethers, part 6: Complexes of Cryptand (2, 2, 2) and Kryptofix 5 with some acceptors

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