CAS 881386-01-2 | 3,3-Dichloro-1-(4-nitrophenyl)piperidin-2-one
Molecular Formula: C11H10Cl2N2O3
Molecular Weight: 289.11
EINECS: 813-183-4
Purity: 97% Min.
Package: 1 g / 5 g / 25 g / 100 g / 1 kg / 25 kg
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Product Introduction
Introduction
3,3-Dichloro-1-(4-nitrophenyl)-2-piperidinone is an important pharmaceutical intermediate, such as it can be used to prepare apixaban derivatives. Apixaban is a small molecule selective FXa inhibitor of pyrazole derivatives.
Specification of CAS 881386-01-2 | 3,3-Dichloro-1-(4-nitrophenyl)piperidin-2-one
ITEMS | SPECIFICATION |
Boiling point | 520.2 °C |
pka | -7.38 |
storage temp. | Sealed in dry,2-8°C |
density | 1.50 |
Synthesis of CAS 881386-01-2 | 3,3-Dichloro-1-(4-nitrophenyl)piperidin-2-one
Conditions
With phosphorus pentachloride In chlorobenzene at 55℃; for 5h;
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