CAS 845267-78-9 | TERT-BUTYL 2,4-DIOXOPIPERIDINE-1-CARBOXYLATE

Introduction
2,4-Dipiperidone-1-carboxylate tert-butyl ester is a reactant in the synthesis of phenoxymethyl-dihydrothiazolopyridone derivatives as a choice for metabotropic glutamate 5 (mGlu5) receptors Sexual orthosteric modulators (PAMs).

Specification of CAS 845267-78-9 | TERT-BUTYL 2,4-DIOXOPIPERIDINE-1-CARBOXYLATE

Synthesis of CAS 845267-78-9 | TERT-BUTYL 2,4-DIOXOPIPERIDINE-1-CARBOXYLATE

Conditions

In ethyl acetate for 3h; Reflux;

Reference

Butler, Jeffrey D.; Coffman, Keith C.; Ziebart, Kristin T.; Toney, Michael D.; Kurth, Mark J.

[Chemistry - A European Journal, 2010, vol. 16, # 30, p. 9002 - 9005]

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