CAS:71989-31-6 | Fmoc-Pro-OH

Name:Fmoc-Pro-OH

Synonyms:Fmoc-L-proline

CAS:71989-31-6

Purity:99%

Molecular Formula:C₂₀H₁₉NO₄

Molecular Weight:337.38

Melting Point:113-117°

Boiling Point:N/A

Density:1.2486 g/cm³(rough estimate)

Appearance:White to off-white (Solid)

Solubility:Soluble in methanol. (almost transparency)

pKa:3.95±0.20(Predicted)

refractive index:-32.5 ° (C=1, DMF)

Storage condition:Store at 2-8°C. Incompatible with oxidizing agents.

Application:Fmoc-Pro-OH(CAS:71989-31-6) is used as pharmaceutical intermediate. Fmoc method is used for the synthesis of the new polymeric support for the preparation of C-terminal peptide amides.

Reference: 

Peter Sieber. A new acid-labile anchor group for the solid-phase synthesis of C-terminal peptide amides by the Fmoc method. Tetrahedron Lett. 1987, 28 (19),2107-2110 .

Bin Zou.; Jingjun Wei.; Guorong Cai.; Dawei Ma. Synthesis of an Oxazoline Analogue of Apratoxin A. Org. Lett. 2003, 5 (19),3503-3506 .

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