CAS:6627-55-0 | 2-Bromo-4-methylphenol
Molecular Formula:C7H7BrO
Molecular Weight:187.03 g/mol
EINECS:229-595-7
Purity:97%
Package:5g/10g/25g/50g/bulk package
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Product Introduction
Name | 2-Bromo-4-methylphenol |
Synonyms | 2-Bromo-p-cresol;2-Bromo-4-cresol;3-Bromo-4-hydroxytoluene; NSC 60115 |
CAS | 6627-55-0 |
MDL No | MFCD00002151 |
Boiling Point | 214 °C |
Melting Point | 16 °C |
Flash Point | >110°(230°F) |
Density | 1.547g/ml |
Specific Gravity (20/20) | 1.53 |
PSA | 20.23 |
LogP | 2.93 |
Appearance | Colorless to yellow liquid |
Sensitivity | Air Sensitive |
Solubility | Chloroform, Methanol;Slightly soluble in water |
Vapour Pressure | 0.1±0.4 mmHg at 25°C |
Refractive index | 1.58 |
Storage condition | Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition |
Applications:2-Bromo-4-methylphenol(CAS:6627-55-0) is a useful synthetic intermediate. It was used in the synthesis of furan-2-ylmethylene thiazolidinediones as potent, and selective inhibitors of phosphoinositide 3-kinase γ. It was also a reactant used to prepare phosphoramidate and phosphorothioamidate analogs of amiprophos Me as potential antimalarial agents.
References:Pomel, V., et al.: J. Med. Chem., 49, 3857 (2006); Mara, C., et al.: Bioorg. Med. Chem. Lett., 21, 6180 (2011)
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