CAS:613-93-4 | N-Methylbenzamide

Name:N-Methylbenzamide

Synonyms:N-METHYLBENZAMIDE;n-methyl-benzamid;

N-Methylbenzenamide;n-methylbenzenecarboxamide

CAS:613-93-4

Purity:98%

MDL No:MFCD00011642

Molecular Formula:C₆H₅CONHCH₃

Molecular Weight:135.16

Melting Point:76-78°C 

Boiling Point:167°C/11mmHg

EINECS:210-362-3

Density:1.1031g/cm³ (rough estimate)

Appearance:White Solid

Solubility:ethanol: soluble50mg/mL, clear, yellow-green

Water solubility:Insoluble in water

pKa:15.00±0.46(Predicted)

refractive index:1.5589 (estimate)

Storage condition:Sealed in dry,Room Temperature

Packaging & Delivery

Package:5g/10g/25g/50g/bulk package

Transportation: by FeDex or by ocean shipping or clients requirement

Delivery Detail: Within 3-5 days after full payment

Flexible payment terms: support T/T, Paypal , Credit Card

Application:N-Methylbenzamide(CAS:613-93-4) acts as a potent PDE10A (phosphodiesterase with a remarkable localization as the protein is abundant only in brain tissue) inhibitor. It is also employed as a pharmaceutical intermediate.

Reference: 

John Paul Kilburn.; Jan Kehler.; Morten Langgård.; Mette N. Erichsen.; Sebastian Leth-Petersen.; Mogens Larsen.; Claus Tornby Christoffersen.; Jacob Nielsen. N-Methylanilide and N-methylbenzamide derivatives as phosphodiesterase 10A (PDE10A) inhibitors.Bioorg Med Chem.,2010,21(19), 6053-6062.

Walter H. Puterbaugh.; Charles R. Metalation of N-Methylbenzamide with Excess n-Butyllithium. Condensations with Electrophilic Compounds to Form ortho Derivatives. Cyclizations.J. Org. Chem.,1964,29(4), 853-856.

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