CAS:23828-92-4 | Ambroxol Hydrochloride
Molecular Formula:C13H18Br2N2O•HCl
Molecular Weight:414.56g/mol
Purity:98%
Package:5g/10g/25g/50g/bulk package
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Product Introduction
Applications
Ambroxol hydrochloride(CAS:23828-92-4) is a small molecule expectorant and mucolytic agent with antioxidant and antiinflammatory effects. Ambroxol stimulates the secretion of surfactant which decreases mucus adhesion to the bronchial lining and produces expectorant effects. The antioxidant effects of Ambroxol are well demonstrated, where lipid peroxidation initiated by t-butyl hydroperoxide or doxorubicin is suppressed in the presence Ambroxol, and scavenging of hydroxyl radicals and cellular superoxide radical anions is also observed. Ambroxol produces antiinflammatory effects by blocking the expression of proinflammatory messengers, inhibiting the release of histamine from mast cells and the generation of cytokines and interleukins. Ambroxol hydrochloride is an inhibitor of Sodium Channel Protein.
Specification
|
ITEMS |
SPECIFICATION |
|
IUPAC Name |
4-[(2-amino-3,5-dibromophenyl)methylamino]cyclohexan-1-ol;hydrochloride |
|
MDL No |
MFCD00078932 |
|
Boiling Point |
468.6ºC at 760 mmHg |
|
Melting Point |
>235°C (dec.) |
|
Flash Point |
237.2ºC |
|
PSA |
58.28 |
|
LogP |
4.96 |
|
Appearance |
White to off-white (Solid) |
|
Solubility |
Soluble in methanol, water (~5 mg/ml), ethanol (~5 mg/ml), and DMSO (50 mM). Insoluble in ether |
|
Storage condition |
2-8°C, sealed storage, away from moisture |
|
InChI |
InChI=1S/C13H18Br2N2O.ClH/c14-9-5-8(13(16)12(15)6-9)7-17-10-1-3-11(18)4-2-10;/h5-6,10-11,17-18H,1-4,7,16H2;1H |
|
InChIKey |
QNVKOSLOVOTXKF-UHFFFAOYSA-N |
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