CAS:393-55-5 | 2-Fluoronicotinic Acid

Name:2-Fluoronicotinic acid

Synonyms:2-Chloro-1,3-dinitro-5-(trifluoromethyl)benzene;

3,5-dinitro-4-chloro-alpha,alpha,alpha-trifluorotoluene;

Benzene, 2-chloro-1,3-dinitro-5- (trifluoromethyl)-;

Benzene, 2-chloro-1,3-dinitro-5-(trifluoromethyl)-;

Toluene, 4-chloro-.alpha.,.alpha.,.alpha.-trifluoro-3,5-dinitro-;

2-Fluoro-3-NicotinicAcid;

2-Fluoropyridine-3-carboxylic acid;

Acide 2-fluoropyridine-3-carboxylique;

3-Pyridinecarboxylic acid, 2-fluoro-;

2-Fluoro-Nicotinic Acid;

CAS:393-55-5

Purity:98%

MDL No:MFCD00040744

Molecular Formula:C6H4FNO2

Molecular Weight:141.1

Melting Point:161-165 °C(lit.)

Boiling Point:278.6°C at 760 mmHg

Flash Point:122.3°C

EINECS:206-888-8

Density:1.706g/cm3

Appearance:White to off-white (Solid)

pKa:2.54±0.10(Predicted)

Vapor Presure:0.00713mmHg at 25°C

refractive index:1.533

Storage condition:Keep in dark place,Sealed in dry,Room Temperature

InChIKey:LLLVHTWJGWNRBD-UHFFFAOYSA-N

Application:2-Fluoronicotinic Acid is an intermediate used to prepare oxadiazole derivatives to inhibit tubulin polymerization and to cause mitotic arrest in tumor cells. It is also used to synthesize potent and selective inhibitors of human reticulocyte 15-lipoxygenase-1.

Reference: 

Ouyang, X., et al.: Bioorg. Med. Chem. Lett., 16, 1191 (2006); Rai, G., et al.: J. Med. Chem., 53, 7392 (2010)

Packaging & Delivery

Package:5g/10g/25g/50g/bulk package

Transportation: by FeDex or by ocean shipping or clients requirement

Delivery Detail: Within 3-5 days after full payment

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