CAS 1158984-94-1 | 1-(tert-Butoxycarbonyl)pyrrole-2-boronic Acid MIDA Ester
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CAS 1158984-94-1 | 1-(tert-Butoxycarbonyl)pyrrole-2-boronic Acid MIDA Ester

CAS 1158984-94-1 | 1-(tert-Butoxycarbonyl)pyrrole-2-boronic Acid MIDA Ester

Molecular Formula: C14H19BN2O6
Molecular Weight: 322.12146
Purity: 97% Min.
Package: 1 g / 5 g / 25 g / 100 g / 1 kg / 25 kg

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Product Introduction

Specification of CAS 1158984-94-1 | 1-(tert-Butoxycarbonyl)pyrrole-2-boronic acid MIDA ester

ITEMS

SPECIFICATION

Melting point

166-171℃

Synthesis of CAS 1158984-94-1 | 1-(tert-Butoxycarbonyl)pyrrole-2-boronic acid MIDA ester

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Conditions

Stage #1: N-tert-butyloxycarbonyl-pyrrole With n-butyllithium; Triisopropyl borate; N-ethyl-N,N-diisopropylamine In tetrahydrofuran; hexane at -78 - 20℃;

Stage #2: N-methyliminodiacetic acid In dimethyl sulfoxide at 75℃; under 1 Torr; for 2h;

Reference

Knapp, David M.; Gillis, Eric P.; Burke, Martin D.

[Journal of the American Chemical Society, 2009, vol. 131, p. 6961 - 6963]

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