CAS:2156-56-1 | Sodium Dichloroacetate

Name:Sodium dichloroacetate

Synonyms:Dichloroacetic Acid Sodium Salt;CPC 211; Ceresine; DCA; Dichloroacetic Acid Sodium Salt; Sodium Dichloroacetate

CAS:2156-56-1

Purity:98%

MDL No:MFCD00070489

Molecular Formula:C₂HCl₂NaO₂

Molecular Weight:150.92

Melting Point:N/A

Boiling Point:194° C at 760 mmHg

EINECS:218-461-3

PSA:40.1

LogP: 0.92

Appearance:White - Almost white Crystal - Powder

Sensitivity:Moisture sensitive

Stability:Hygroscopic

Solubility:Methanol (Slightly), Water (Slightly)

Water solubility:soluble in cold water

Storage condition:Inert atmosphere,2-8°C

InChI:InChI=1S/C2H2Cl2O2.Na/c3-1(4)2(5)6;/h1H,(H,5,6)

InChIKey:InChIKey=ZOXHFYPCZQICQD-UHFFFAOYSA-N

Application:Sodium dichloroacetate(CAS:2156-56-1) has been shown to have numerous effects on pathways of intermediary metabolism. Experiments have reported the compound to inhibit gluconeogenesis and stimulate peripheral glucose utilization. It has additionally been found to facilitate oxidation of lactate via increase in activity of pyruvate dehydrogenase. This agent also demonstrates the ability to inhibit lipogenesis and cholesterolgenesis, as well as its own metabolism. Furthermore, assays have found sodium dichloroacetate to improve cardiac output and left ventricular mechanical efficiency via facilitation of myocardial metabolism of lactate and carbohydrate as opposed to fat. Other studies suggest that sodium dichloroacetate inhibits tumor growth and may decrease proliferation and induce apoptosis in cancer cell lines. Sodium dichloroacetate is an inhibitor of PDK.

Reference: 

1. Stacpoole, P.W. 1989. Metab. Clin. Exp. 38: 1124-1144. PMID: 2554095

2. Kimura, S., et al. 1997. Brain Dev. 19: 535-540. PMID: 9440797

3. Bonnet, S., et al. 2007. Cancer Cell. 11: 37-51. PMID: 17222789

Packaging & Delivery

Package:500g/1kg/5kg/10kg/bulk package

Transportation: by FeDex or by ocean shipping or clients requirement

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