CAS 771-69-7 | 1,2,3-Trifluoro-4-nitrobenzene
Molecular Formula: C6H2F3NO2
Molecular Weight: 177.08
EINECS: 212-238-4
Purity: 97% Min.
Package: 100 g / 1 kg / 25 kg
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Product Introduction
Introduction
1,2,3-Trifluoro-4-nitrobenzene is mainly used for the synthesis of a new generation of fluoroquinolone antibacterial drug ofloxacin (ofloxacin). It can also be used to synthesize quinone acid antibacterial drugs such as lomefloxacin.
Specification of CAS 771-69-7 | 1,2,3-Trifluoro-4-nitrobenzene
ITEMS | SPECIFICATION |
Storage temp. | Sealed in dry,Room Temperature |
Fp | 200 °F |
Refractive index | n20/D 1.492(lit.) |
Density | 1.541 g/mL at 25 °C (lit.) |
Boiling point | 92 °C/20 mmHg (lit.) |
Specific Gravity | 1.541 |
BRN | 2449746 |
CAS DataBase Reference | 771-69-7(CAS DataBase Reference) |
Synthesis of CAS 771-69-7 | 1,2,3-Trifluoro-4-nitrobenzene
Conditions
Stage #1: 4-nitro-1,2,3-trichlorobenzene With potassium fluoride; tetrabutylammomium bromide In dimethyl sulfoxide at 75 - 80℃; for 4h;
Stage #2: With potassium fluoride; tetrabutyl ammonium fluoride In dimethyl sulfoxide at 75 - 180℃; for 12h; Time;
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