CAS:1206161-97-8丨Filgotinib
Molecular Formula: C21H23N5O3S
Molecular Weight: 425.5
Purity: 98%
Package:0.1g 0.25g 1g 5g 10g 25g
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Product Introduction
Products Description
A highly effective and selective JAK1 inhibitor can effectively inhibit the activity of JAK1, JAK2, JAK3 and TYK2 with IC50 values of 10nM, 28nM, 810nM and 116nM, respectively.FilgotinibisapotentandselectiveJAK1inhibitor.ItisconsideredapromisingagentasitinhibitsJAK1selectively.Filgotinibdisplayedaselectivityof30-foldforChemicalbookJAK1-overJAK2-dependentsignaling.GLPG0634dose-dependentlyinhibitedTh1andTh2differentiationandtoalesserextentthedifferentiationofTh17cellsinvitro.
CAS:1206161-97-8
Specification
|
ITEMS |
SPECIFICATION |
| Appearance | solid |
| Color | Off-white |
|
Melting point |
229 - 231°C |
|
CAS |
1206161-97-8 |
|
Density |
1.51±0.1 g/cm3(Predicted) |
| Storage condition | -20°C |
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