CAS 632365-54-9 | 1H-Pyrazole-3-carboxylicacid,5-amino-,methylester
Molecular Formula: C5H7N3O2
Molecular Weight: 141.13
Purity: 97% Min.
Package: 1 g / 5 g / 25 g / 100 g / 1 kg / 25 kg
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Product Introduction
Introduction
5-amino-1H-pyrazole-3-carboxylate methyl ester is a carboxylate derivative, which is an intermediate for synthesizing a drug for treating cardiovascular diseases.
Specification of CAS 632365-54-9 | 1H-Pyrazole-3-carboxylicacid,5-amino-,methylester
ITEMS | SPECIFICATION |
Melting point | 135～136℃ |
Storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
Density | 1.395 g/cm3 |
Boiling point | 397.8 °C |
pka | 12.32 |
CAS DataBase Reference | 632365-54-9 |
Synthesis of CAS 632365-54-9 | 1H-Pyrazole-3-carboxylicacid,5-amino-,methylester
Conditions
Stage #1: 5-nitro-1H-pyrazole-3-carboxylic acid methyl ester With hydrogen; acetic acid; palladium 10% on activated carbon In tetrahydrofuran at 20℃; for 144h;
Stage #2: With sodium hydrogencarbonate In dichloromethane
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