CAS 505084-59-3 | 2-Chloro-5-(trifluoromethyl)-3-pyridinecarboxylic Acid
Molecular Formula: C7H3ClF3NO2
Molecular Weight: 225.55
Purity: 97% Min.
Package: 1 g / 5 g / 25 g / 100 g / 1 kg
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Product Introduction
Introduction
2-Chloro-5-(trifluoromethyl)-3-pyridinecarboxylic acid is a fluorine-containing pyridine intermediate
Specification of CAS 505084-59-3 | 2-Chloro-5-(trifluoromethyl)-3-pyridinecarboxylic acid
ITEMS | SPECIFICATION |
Melting point | 281℃ |
InChIKey | RMSKYTKOFDQVEL-UHFFFAOYSA-N |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
form | Solid |
density | 1.603 g/cm3 |
Boiling point | 301.5 °C |
pka | 1.57 |
Synthesis of CAS 505084-59-3 | 2-Chloro-5-(trifluoromethyl)-3-pyridinecarboxylic acid
Conditions:
With n-butyllithium In tetrahydrofuran; hexane at -75℃; for 0.25h;
Reference:
Cottet, Fabrice; Marull, Marc; Lefebvre, Olivier; Schlosser, Manfred
[European Journal of Organic Chemistry, 2003, # 8, p. 1559 - 1568]
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