CAS 43229-01-2 | 2-Bromo-4'-Benzyloxy-3'-nitroacetophenone
Molecular Formula: C15H12BrNO4
Molecular Weight: 350.16
EINECS: 610-115-3
Purity: 97% Min.
Package: 1 g / 5 g / 25 g / 100 g / 1 kg / 25 kg
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Product Introduction
Introduction
3'-Nitro-4'-benzyloxy-2-bromoacetophenone is a key intermediate of formoterol, a long-acting selective adrenergic β2 agonist with Chemicalbook has a bronchodilator effect, and in a dose-dependent manner, increases forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), and peak expiratory flow (PER).
Specification of CAS 43229-01-2 | 2-Bromo-4'-Benzyloxy-3'-nitroacetophenone
ITEMS | SPECIFICATION |
Melting point | 135-137 °C |
storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
solubility | Soluble in Methylene chloride, sparingly soluble in ethyl acetate, insoluble in water |
color | Pale yellow to cream coloured crystalline powder |
density | 1.517 g/cm3 |
Boiling point | 465.2 °C |
CAS DataBase Reference | 43229-01-2(CAS DataBase Reference) |
Synthesis of CAS 43229-01-2 | 2-Bromo-4'-Benzyloxy-3'-nitroacetophenone
Conditions
With N,N,N-trimethylanilinium bromide In dichloromethane at 300℃; for 4h;
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