CAS:147126-75-8 | Emtricitabine Menthyl Ester

Name:Emtricitabine Menthyl Ester

Synonyms:(2S,5R)-(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolane-2-carboxylate;(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl (2S,5S)-5-hydroxy-1,3-oxathiolane-2-carboxylate;

CAS:147126-75-8

Purity:98%

Molecular Formula:C₁₈H₂₆FN₃O₄S

Molecular Weight:399.48

Melting Point:180 - 183°C (dec.)

Boiling Point:508.5±60.0 °C(Predicted)

Density:1.47g/cm³

PSA:121.74

LogP:3.14

Appearance:White to Off-White Solid

Stability:Hygroscopic

Solubility:Chloroform (Slightly), Methanol (Slightly)

pKa:2.40±0.10(Predicted)

Storage condition:Hygroscopic, Refrigerator, under inert atmosphere

Application:Emtricitabine Menthyl Ester(CAS:147126-75-8) is an impurity of Emtricitabine (E525000). Emtricitabine is a reverse transcriptase inhibitor. It is an effective antiviral agent against HIV, HBV, and other viruses replicating in a similar manner. A nucleoside analog structurally related to Lamivudine (L172500).

Reference: 

FASEB J., 13, 1511 (1999), Molina, J.-M., et al.: J. InfecSchinazi, R.F., et al.: Antimicrob. Ag. Chemother., 36, 2423 (1992), Shockeor, J.P., et al.: Xenobioica, 26, 189 (1996), Feng, J.Y., et al.: . Dis., 182, 599 (2000)

Packaging & Delivery

Package:5g/10g/25g/50g/bulk package

Transportation: by FeDex or by ocean shipping or clients requirement

Delivery Detail: Within 3-5 days after full payment

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