CAS:24905-71-3 | Guanosine 5′-(tetrahydrogen Triphosphate) Sodium Salt

Name:Guanosine 5′-(tetrahydrogen triphosphate) Sodium Salt

Synonyms:5′-GTP Sodium Salt

CAS:24905-71-3

Purity:97%

Molecular Formula:C₁₀H₁₅N₅NaO₁₄P₃

Molecular Weight:545.16

Melting Point:>238° C (dec.)

Boiling Point:1028.3ºC at 760mmHg

Flash Point:575.7ºC

PSA:331.36

Water solubility:50 mg/mL

Storage condition:Store at -20° C

Application:Guanosine 5′-(tetrahydrogen triphosphate) Sodium Salt(CAS:24905-71-3) is a salt of the GTP substrate used in RNA synthesis and DNA replicaiton. It is also used as a source of energy for protein synthesis. In gluconeogenesis, it is also used as a source of energy. In G protein-related signal transduction, it is essential.

Reference: 

1. Ohta, T., Sarkar, S., and Thach, R.E.The role of guanosine 5′-triphosphate in the initiation of peptide synthesis. III. Binding of formylmethionyl-tRNA to ribosomes. Proc. Nat. Acad. Sci. USA 58(4), 1638-1644 (1967).

2. Hanson, R.W., and Garber, A.J.Phosphoenolpyruvate carboxykinase. I. Its role in gluconeogenesis. Am. J. Clin. Nutr. 25(10), 1010-1021 (1972).

3. Neer, E.J.G proteins: Critical control points for transmembrane signals. Protein Sci. 3(1), 3-14 (1994).

4. Berg, JM. et al.: Biochemistry(5th ed).476 (2002); Sepuri, N., et al.: J. Bio. Chem., 273, 1420; 

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